CCVC Seminar Series - Brett Colson, PhD | University of Arizona

Title: “Cardiac Myosin-Binding Protein C: From Sarcomere Regulation to Drug Discovery”

Learning Objectives:

1. Describe the role of cMyBP-C in cardiac contraction and disease.
2. Explain how phosphorylation and HCM mutations alter cMyBP-C structure and function.
3. Discuss the rationale and emerging approaches for small molecule targeting of cMyBP-C.